| # | Swimmer | Team | Seed | Time | Diff |
| 1 |
Lee, Meghan R (17)
|
MDEST |
4:37.72 |
4:30.24 |
-7.48 |
| 2 |
Ghine, Danielle I (16)
|
MDEST |
4:47.99 |
4:38.36 |
-9.63 |
| 3 |
Florio, Rachel V (17)
|
MDEST |
4:29.09 |
4:44.33 |
15.24 |
| 4 |
Serino, Grace M (15)
|
MDEST |
4:50.33 |
4:51.13 |
0.80 |
| 5 |
Dopson, Mia B (15)
|
MDEST |
5:02.44 |
4:58.35 |
-4.09 |
| 6 |
Bendel, Jane A (18)
|
MDRAC |
4:57.33 |
5:00.28 |
2.95 |
| 7 |
Baldinazzo, Natalina (16)
|
MDRAC |
4:55.85 |
5:03.11 |
7.26 |
| 8 |
Corb, Alyssa L (16)
|
MDRAC |
4:57.39 |
5:04.48 |
7.09 |
| 9 |
Alexander, Sarah E (15)
|
MDRAC |
4:59.97 |
5:04.97 |
5.00 |
| 10 |
Onyenorah, Savannah G (16)
|
MDRAC |
4:46.11 |
5:09.24 |
23.13 |
| 11 |
Kidd, Anna B (17)
|
MDRAC |
5:02.31 |
5:10.62 |
8.31 |
| 12 |
Snyder, Alexandra M (16)
|
MDRAC |
5:17.30 |
5:13.67 |
-3.63 |
| 13 |
Charles, Sarah L (16)
|
MALAC |
|
5:17.80 |
- |
| 14 |
Daniel, Deborah J (15)
|
MDRAC |
5:23.49 |
5:21.95 |
-1.54 |
| 15 |
Gunawardane, Sonali (16)
|
MDEST |
5:21.69 |
5:32.14 |
10.45 |
| 16 |
Hocker, Lydia C (15)
|
MALAC |
|
5:32.65 |
- |
| 17 |
Mazur, Karolina T (15)
|
MDEST |
5:35.78 |
5:41.55 |
5.77 |